Cytotoxicity

This assay is used to evaluate the cytotoxicity (cellular toxicity) of the material to be examined. It is designed to determine the biological response of mammalian cells in the extracorporeal environment using appropriate biological parameters. In this experiment, after the exposure time of the cell culture to the material, evaluation of the presence and degree of cytotoxic effect is made. At the conclusion stage, measurements can be made in different categories. These categories are:

• Evaluation of cell damage by morphological means,
• Measuring cell damage
• Measuring cell proliferation,
• Measuring certain properties of cell metabolism